Start a two player game, with only one actual player. Throw a perfect game, striking out every batter. Save the game in the bottom of the ninth inning with two strikes and two outs. Finish the game, collect your points, and save the options. Reload the game and repeat to collect the points again.
Change to the team that you are facing and make them play poorly, allowing your original team to score a lot of runs. In the last inning, switch back to your team and claim your team's cheaply made points.
Hint: Easy homeruns:
When controlling Barry Bonds at bat, press the Square so that you are on "Power" and not "Contact". When you are on "Power", only the yellow box will appear, and when you are on "Contact", there will be a shaded area covering the yellow box. If the pitch is up and in, move the box there and swing. It will almost always be an automatic homerun.
Hint: Free balls:
If you are down in the count or need a quick ball, pretend to lay down a bunt. Pull back while the pitcher is in his motion. This should result in a ball being thrown. Note: This only works up to two times in an at bat.
Hint: Change jerseys in franchise mode:
Before playing in a franchise mode game, go to quick play, and on the team's options highlight "Change Uniform". Go back, exit quick play, load the franchise, and when you get to the play game screen on options, your pointer will be on the blacked out uniform part. Press X and you can change uniforms. Once you change lineups or pitchers, this option is no longer available; it only works for that one game.
Glitch: Late swing:
When you are at bat, for some reason when you press Swing, the player will actually swing a moment after it is pressed resulting in a swing and a miss. You should press Swing in advance, preferably after the pitcher releases the ball.